{"id":7346,"date":"2023-05-05T16:30:36","date_gmt":"2023-05-05T23:30:36","guid":{"rendered":"https:\/\/www.promisdx.com\/?page_id=7346"},"modified":"2023-06-01T09:24:10","modified_gmt":"2023-06-01T16:24:10","slug":"rd","status":"publish","type":"page","link":"https:\/\/www.promisdx.com\/?page_id=7346","title":{"rendered":"Research & Development"},"content":{"rendered":"

[vc_row full_width=”stretch_row_content_no_spaces” video_bg=”yes” video_bg_url=”” css=”.vc_custom_1679006842190{margin-bottom: 20px !important;background-image: url(https:\/\/www.promisdx.com\/wp-content\/uploads\/2022\/11\/PXL_20221115_222432685.PORTRAIT2-scaled.jpg?id=5558) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}” el_class=”margin cover”][vc_column][vc_custom_heading text=”Research & Development” font_container=”tag:h2|text_align:left|color:%23ffffff” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” el_class=”size min-txt-main-head”][\/vc_column][\/vc_row][vc_section el_id=”overview”][vc_row content_placement=”middle” css=”.vc_custom_1677545430759{margin-top: 20px !important;margin-bottom: 20px !important;}”][vc_column][vc_custom_heading text=”Overview” font_container=”tag:h3|text_align:left|color:%23474747″ google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” el_class=”min-txt-body-head”][vc_column_text el_class=”body-text”]<\/p>\n

Promis Diagnostics is focused on validating our proprietary cancer assay via clinical research studies and plan on launching the cancer diagnostic service soon, then expanding to new products and indications. Utilizing a proprietary marker with LTE-qMSP platform, Promis Diagnostics builds its pipeline of diagnostic products for the early detection of other cancers.<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1683680002732{padding-top: 0px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 0px !important;}”][vc_column css=”.vc_custom_1683680062425{padding-top: 0px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 0px !important;}”][vc_single_image image=”7216″ img_size=”975×650″ alignment=”center” onclick=”img_link_large” el_class=”border”][\/vc_column][\/vc_row][\/vc_section][vc_section full_width=”stretch_row_content” el_class=”colon-bg” css=”.vc_custom_1679346144484{padding-top: 3rem !important;padding-bottom: 3rem !important;}”][vc_row el_class=”margin”][vc_column width=”1\/2″ offset=”vc_col-xs-12″][vc_custom_heading text=”Bladder Cancer” font_container=”tag:h2|text_align:center|color:%231670bf” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” link=”url:https%3A%2F%2Fbmccancer.biomedcentral.com%2Farticles%2F10.1186%2Fs12885-022-10275-2||target:%20_blank|” el_class=”min-txt-num-head underline-on-hover”][vc_row_inner][vc_column_inner width=”1\/2″ offset=”vc_col-xs-6″][vc_custom_heading text=”90%” font_container=”tag:h2|text_align:center|color:%231670bf” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” css_animation=”appear” el_class=”min-txt-num-head” css=”.vc_custom_1682559937558{margin-top: 0px !important;margin-bottom: 0px !important;border-top-width: 0px !important;border-bottom-width: 0px !important;padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column_text el_class=”body-text”]<\/p>\n

Sensitivity<\/strong><\/span><\/h6>\n

[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″ offset=”vc_col-xs-6″][vc_custom_heading text=”94%” font_container=”tag:h2|text_align:center|color:%231670bf” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” css_animation=”appear” el_class=”min-txt-num-head” css=”.vc_custom_1682529483693{margin-top: 0px !important;margin-bottom: 0px !important;border-top-width: 0px !important;border-bottom-width: 0px !important;padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column_text el_class=”body-text”]<\/p>\n

Specificity<\/strong><\/span><\/h6>\n

[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=”1\/2″ offset=”vc_col-xs-12″][vc_column_text el_class=”body-text”]<\/p>\n

Promis Diagnostics’ bladder cancer test<\/strong> is a urine test, aimed at early detection of bladder cancer in patients. This test is a non-invasive method to analyze tumor markers in the urine of patients with hematuria and to identify patients at both low and high risk of bladder cancer. Our real time PCR-based methylation assay is a promising test to early detection of bladder cancer.<\/span><\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section full_width=”stretch_row_content” el_class=”bladder-bg” css=”.vc_custom_1679346129700{padding-top: 3rem !important;padding-bottom: 3rem !important;}”][vc_row el_class=”margin”][vc_column width=”1\/2″ offset=”vc_col-xs-12″][vc_column_text el_class=”body-text”]<\/p>\n

Promis Diagnostics’ colon cancer test<\/strong> is a stool-based test for screening and diagnosis of cancer. The assay is designed to be an easy, accurate, and affordable early colorectal cancer detection test. The test detects methylation of DNA specific to adenomatous polyps and colon cancer. In a clinical study, our colon test gave an overall sensitivity of 90.2% with a specificity of 90.2%.<\/span><\/p>\n

[\/vc_column_text][\/vc_column][vc_column width=”1\/2″ offset=”vc_col-xs-12″][vc_custom_heading text=”Colon Cancer” font_container=”tag:h2|text_align:center|color:%23f77f00″ google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” link=”url:https%3A%2F%2Fclinicalepigeneticsjournal.biomedcentral.com%2Farticles%2F10.1186%2Fs13148-019-0642-0||target:%20_blank|” el_class=”min-txt-num-head underline-on-hover”][vc_row_inner][vc_column_inner width=”1\/2″ offset=”vc_col-xs-6″][vc_custom_heading text=”90%” font_container=”tag:h2|text_align:center|color:%23f77f00″ google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” css_animation=”appear” el_class=”min-txt-num-head” css=”.vc_custom_1682528960494{margin-top: 0px !important;margin-bottom: 0px !important;border-top-width: 0px !important;border-bottom-width: 0px !important;padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column_text el_class=”body-text”]<\/p>\n

Sensitivity<\/strong><\/span><\/h6>\n

[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″ offset=”vc_col-xs-6″][vc_custom_heading text=”90%” font_container=”tag:h2|text_align:center|color:%23f77f00″ google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” css_animation=”appear” el_class=”min-txt-num-head” css=”.vc_custom_1682528972534{margin-top: 0px !important;margin-bottom: 0px !important;border-top-width: 0px !important;border-bottom-width: 0px !important;padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column_text el_class=”body-text”]<\/p>\n

Specificity<\/strong><\/span><\/h6>\n

[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][\/vc_section][vc_section full_width=”stretch_row_content” el_class=”lung-bg” css=”.vc_custom_1679346108897{padding-top: 3rem !important;padding-bottom: 3rem !important;}”][vc_row el_class=”margin”][vc_column width=”1\/2″ offset=”vc_col-xs-12″][vc_custom_heading text=”Lung Cancer” font_container=”tag:h2|text_align:center|color:%231670bf” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” link=”url:https%3A%2F%2Fclinicalepigeneticsjournal.biomedcentral.com%2Farticles%2F10.1186%2Fs13148-019-0642-0||target:%20_blank|” el_class=”min-txt-num-head underline-on-hover”][vc_row_inner][vc_column_inner width=”1\/2″ offset=”vc_col-xs-6″][vc_custom_heading text=”78%” font_container=”tag:h2|text_align:center|color:%231e73be” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” css_animation=”appear” el_class=”min-txt-num-head” css=”.vc_custom_1677547548188{margin-top: 0px !important;margin-bottom: 0px !important;border-top-width: 0px !important;border-bottom-width: 0px !important;padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column_text el_class=”body-text”]<\/p>\n

Sensitivity<\/strong><\/span><\/h6>\n

[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″ offset=”vc_col-xs-6″][vc_custom_heading text=”92%” font_container=”tag:h2|text_align:center|color:%231e73be” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” css_animation=”appear” el_class=”min-txt-num-head” css=”.vc_custom_1677547557009{margin-top: 0px !important;margin-bottom: 0px !important;border-top-width: 0px !important;border-bottom-width: 0px !important;padding-top: 0px !important;padding-bottom: 0px !important;}”][vc_column_text el_class=”body-text”]<\/p>\n

Specificity<\/strong><\/span><\/h6>\n

[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=”1\/2″ offset=”vc_col-xs-12″][vc_column_text el_class=”body-text”]<\/p>\n

Promis Diagnostic’s lung cancer test<\/strong> is a blood test to identify people with a heightened risk of lung cancer for triage into CT scanning. The test is a qualitative detection of epigenetic markers, PCDHGA12, associated with lung cancer in pulmonary nodule patients. It has been proven to diagnose lung cancer with 77.8% sensitivity and specificity of 92.3% in a pivotal study on 522 subjects.<\/span><\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section][vc_section el_id=”technology”][vc_row full_width=”stretch_row_content_no_spaces” css=”.vc_custom_1683328920953{margin-top: 3vw !important;padding-top: 1vw !important;padding-bottom: 1vw !important;}” el_class=”margin”][vc_column][vc_empty_space height=”15vw” el_class=”vl” css=”.vc_custom_1683142130393{margin-left: 50% !important;border-left-width: 2px !important;border-left-color: #f2f2f2 !important;border-left-style: solid !important;}”][\/vc_column][\/vc_row][vc_row full_width=”stretch_row_content_no_spaces” equal_height=”yes” content_placement=”middle” el_class=”cover”][vc_column width=”2\/5″ offset=”vc_col-xs-2\/5″][vc_empty_space height=”” el_class=”dna” css=”.vc_custom_1683221228996{background-image: url(https:\/\/www.promisdx.com\/wp-content\/uploads\/2023\/05\/DNA_Methylation-2.png?id=7358) !important;background-position: 0 0 !important;background-repeat: no-repeat !important;}”][\/vc_column][vc_column width=”1\/5″ offset=”vc_col-xs-1\/5″][vc_custom_heading text=”DNA Methylation” font_container=”tag:h2|text_align:center|color:%23474747|line_height:1″ google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” el_class=”min-txt-body-head”][\/vc_column][vc_column width=”2\/5″ offset=”vc_col-xs-2\/5″][vc_empty_space height=”” el_class=”dna” css=”.vc_custom_1683221228996{background-image: url(https:\/\/www.promisdx.com\/wp-content\/uploads\/2023\/05\/DNA_Methylation-2.png?id=7358) !important;background-position: 0 0 !important;background-repeat: no-repeat !important;}”][\/vc_column][\/vc_row][vc_row][vc_column][vc_single_image image=”7518″ img_size=”full” alignment=”center” onclick=”img_link_large” css=”.vc_custom_1685636579211{border-top-width: 1px !important;border-right-width: 1px !important;border-bottom-width: 1px !important;border-left-width: 1px !important;padding-top: 10px !important;padding-right: 10px !important;padding-bottom: 10px !important;padding-left: 10px !important;border-left-color: #d1d1d1 !important;border-left-style: solid !important;border-right-color: #d1d1d1 !important;border-right-style: solid !important;border-top-color: #d1d1d1 !important;border-top-style: solid !important;border-bottom-color: #d1d1d1 !important;border-bottom-style: solid !important;}”][\/vc_column][\/vc_row][vc_row equal_height=”yes”][vc_column width=”1\/2″][vc_column_text el_class=”body-text”]<\/p>\n

High detection stability in body fluids DNA is more stable<\/span> than protein and RNA.<\/p>\n

[\/vc_column_text][vc_single_image image=”7519″ img_size=”medium” alignment=”center” css=”.vc_custom_1685636524207{padding-top: 1vw !important;}”][\/vc_column][vc_column width=”1\/2″][vc_column_text el_class=”body-text”]<\/p>\n

Possible to amplify by PCR when a minute amount<\/span> of DNA Methylation Biomarkers exist in body fluids<\/p>\n

[\/vc_column_text][vc_single_image image=”7520″ img_size=”full” alignment=”center”][\/vc_column][\/vc_row][\/vc_section]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row full_width=”stretch_row_content_no_spaces” video_bg=”yes” video_bg_url=”” css=”.vc_custom_1679006842190{margin-bottom: 20px !important;background-image: url(https:\/\/www.promisdx.com\/wp-content\/uploads\/2022\/11\/PXL_20221115_222432685.PORTRAIT2-scaled.jpg?id=5558) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}” el_class=”margin cover”][vc_column][vc_custom_heading text=”Research & Development” font_container=”tag:h2|text_align:left|color:%23ffffff” google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” el_class=”size min-txt-main-head”][\/vc_column][\/vc_row][vc_section el_id=”overview”][vc_row content_placement=”middle” css=”.vc_custom_1677545430759{margin-top: 20px !important;margin-bottom: 20px !important;}”][vc_column][vc_custom_heading text=”Overview” font_container=”tag:h3|text_align:left|color:%23474747″ google_fonts=”font_family:Montserrat%3Aregular%2C700|font_style:700%20bold%20regular%3A700%3Anormal” el_class=”min-txt-body-head”][vc_column_text el_class=”body-text”] Promis Diagnostics is focused on validating our proprietary cancer assay via clinical research studies and plan on launching the […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7346","page","type-page","status-publish","hentry"],"yoast_head":"\nResearch & Development - 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